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We assessed the functional impact of the epistasis signals across a range of functional/-omics datasets identifying significant single-variant eQTLs across brain tissues,。

Epistasis occurs when the phenotype expression of one gene is influenced by another gene. Example: Gene A must be present for Gene B to express a certain trait. Example: The coat color in mice is a classic example。

In classical drama, the epitasis (Ancient Greek: ἐπίτασις) is the main action of a play, in which the trials and tribulations of the main character increase and build toward a climax and dénouement. It is the third and central part when a play is analyzed into five separate parts: prologue, protasis, epitasis, catastasis and catastrophe. In modern dramatic theory, the dramatic arc is oepitasiften referred to, which uses somewhat different di…

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